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WKYMVdM trifluoroacetate salt_Molecular_structure_CAS_)
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WKYMVdM trifluoroacetate salt

Catalog No. W3020 Name Sigma Aldrich
CAS Number Website http://www.sigmaaldrich.com
M. F. C43H62F3N9O9S2 Telephone 1-800-521-8956
M. W. 970.1324896 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154973

SYNONYMS

IUPAC name
(2S)-6-amino-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1R)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]hexanamide; trifluoroacetic acid
IUPAC Traditional name
(2S)-6-amino-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1R)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]hexanamide; trifluoroacetic acid
Synonyms
Trp-Lys-Tyr-Met-Val-D-Met NH2 trifluoroacetate salt trifluoroacetate salt

DATABASE IDS

MDL Number MFCD09039057

PROPERTIES

Empirical Formula (Hill Notation) C41H61N9O7S2 · xC2HF3O2
Purity ≥98% (HPLC)
Apperance white to off-white powder
Solubility H2O: >2 mg/mL
MSDS Link Download
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Trp-Lys-Tyr-Met-Val-D-Met NH2
Biochem/physiol Actions
WKYMVm is a very potent agonist of formyl peptide receptor members FPR1/FPR2 (EC50 1 nM) and FPRL1/FPRL2 (75 pM and 3 nM, respectively). WKYMVm stimulation of leukocytes has been shown to elevate intracellular calcium, induce chemotaxis, superoxide generation, cell killing and phagocytosis.
Description (简体中文)
Amino Acid Sequence
Trp-Lys-Tyr-Met-Val-D-Met NH2
Biochem/physiol Actions
WKYMVm is a very potent agonist of formyl peptide receptor members FPR1/FPR2 (EC50 1 nM) and FPRL1/FPRL2 (75 pM and 3 nM, respectively). WKYMVm stimulation of leukocytes has been shown to elevate intracellular calcium, induce chemotaxis, superoxide generation, cell killing and phagocytosis.

REFERENCES