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PHA 767491 hydrochloride_Molecular_structure_CAS_845538-12-7)
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PHA 767491 hydrochloride

Catalog No. PZ0178 Name Sigma Aldrich
CAS Number 845538-12-7 Website http://www.sigmaaldrich.com
M. F. C12H12ClN3O Telephone 1-800-521-8956
M. W. 249.69618 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154969

SYNONYMS

IUPAC name
2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
IUPAC Traditional name
2-(pyridin-4-yl)-1H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
Synonyms
PHA-00767491 hydrochloride
2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride
1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride

DATABASE IDS

MDL Number MFCD11519962
CAS Number 845538-12-7

PROPERTIES

Empirical Formula (Hill Notation) C12H11N3O · xHCl
Purity ≥98% (HPLC)
Apperance off-white to yellow powder
Solubility H2O: >25 mg/mL
MSDS Link Download
German water hazard class 3

DETAILS

Description (English)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-767491 is a potent and selective ATP-competitive dual inhibitor cdc7/cdk9. PHA-767491 blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites.
Description (简体中文)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-767491 is a potent and selective ATP-competitive dual inhibitor cdc7/cdk9. PHA-767491 blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites.

REFERENCES