PHA 767491 hydrochloride

• Catalog No.: PZ0178
• CAS Number: 845538-12-7
• M. F.: C12H12ClN3O
• M. W.: 249.69618
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
• IUPAC Traditional name: 2-(pyridin-4-yl)-1H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
• Synonyms: PHA-00767491 hydrochloride; 2-Pyridin-4-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one hydrochloride; 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride

DATABASE IDS

• MDL Number: MFCD11519962
• CAS Number: 845538-12-7

PROPERTIES

• Empirical Formula (Hill Notation): C12H11N3O · xHCl
• Purity: ≥98% (HPLC)
• Apperance: off-white to yellow powder
• Solubility: H2O: >25 mg/mL
• German water hazard class: 3

DETAILS

Description (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-767491 is a potent and selective ATP-competitive dual inhibitor cdc7/cdk9. PHA-767491 blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites.

Description (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-767491 is a potent and selective ATP-competitive dual inhibitor cdc7/cdk9. PHA-767491 blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites.