Glabridin

• Catalog No.: G9548
• CAS Number: 59870-68-7
• M. F.: C20H20O4
• M. W.: 324.3704
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-[(3R)-8,8-dimethyl-2H,3H,4H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
• IUPAC Traditional name: glabridin
• Synonyms: 4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl]-1,3-benzenediol; Glabridin; (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol

DATABASE IDS

• Beilstein Number: 7141956
• CAS Number: 59870-68-7
• MDL Number: MFCD03427694

PROPERTIES

• Empirical Formula (Hill Notation): C20H20O4
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Flash Point: 267 °C
• Flash Point: 512.6 °F
• Solubility: DMSO: ≥14 mg/mL
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9.

Description (English)

Biochem/physiol Actions
Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9.