CGS-9343B

• Catalog No.: C1619
• CAS Number: 109826-27-9
• M. F.: C30H32N4O6
• M. W.: 544.59828
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 1-[1-({7-methyl-8-oxa-2-azatricyclo[8.4.0.0^2,^6]tetradeca-1(14),3,5,10,12-pentaen-7-yl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one; but-2-enedioic acid
• IUPAC Traditional name: 1-[1-({7-methyl-8-oxa-2-azatricyclo[8.4.0.0^2,^6]tetradeca-1(14),3,5,10,12-pentaen-7-yl}methyl)piperidin-4-yl]-3H-1,3-benzodiazol-2-one; butenedioic acid
• Synonyms: Zaldaride maleate; CGS9343B; KW-5617; 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]- benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate

DATABASE IDS

• MDL Number: MFCD04113002
• CAS Number: 109826-27-9

PROPERTIES

• Empirical Formula (Hill Notation): C26H28N4O2 · C4H4O4
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Solubility: DMSO: >10 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
CGS-9343B is a selective calmodulin antagonist with minimal protein kinase C or antidopaminergic activity. CGS-9343B is a potent inhibitor of calmodulin-activated (Type I) phosphodiesterase activity with IC50 in the nanomolar range.

Description (简体中文)

Biochem/physiol Actions
CGS-9343B is a selective calmodulin antagonist with minimal protein kinase C or antidopaminergic activity. CGS-9343B is a potent inhibitor of calmodulin-activated (Type I) phosphodiesterase activity with IC50 in the nanomolar range.