Pramipexole dihydrochloride

• Catalog No.: A1237
• CAS Number: 191217-81-9
• M. F.: C10H19Cl2N3S
• M. W.: 284.24896
• Purity: >98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine dihydrochloride
• IUPAC Traditional name: pramipexole dihydrochloride
• Synonyms: PPX dihydrochloride; (S)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride

DATABASE IDS

• MDL Number: MFCD00876894
• CAS Number: 191217-81-9

PROPERTIES

• Empirical Formula (Hill Notation): C10H17N3S · 2HCl
• Purity: >98% (HPLC)
• Apperance: white to off-white powder
• Solubility: H2O: >20 mg/mL
• Storage Condition: desiccated
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Pramipexole is a dopamine agonist active at D3 and D2 receptor subtypes. Pramipexole has been found to have neuroprotective effects independent of its dopamine receptor agonism. It reduces mitochondrial reactive oxygen species (ROS) production and inhibits the activation of apoptotic pathways.

Description (简体中文)

Biochem/physiol Actions
Pramipexole is a dopamine agonist active at D3 and D2 receptor subtypes. Pramipexole has been found to have neuroprotective effects independent of its dopamine receptor agonism. It reduces mitochondrial reactive oxygen species (ROS) production and inhibits the activation of apoptotic pathways.