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Saquinavir mesylate

Catalog No. S8451 Name Sigma Aldrich
CAS Number 149845-06-7 Website http://www.sigmaaldrich.com
M. F. C39H54N6O8S Telephone 1-800-521-8956
M. W. 766.94646 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154946

SYNONYMS

IUPAC name
(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide; methanesulfonic acid
IUPAC Traditional name
methanesulfonic acid; saquinavir
Synonyms
(2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide methanesulfonate
Ro-31-8959

DATABASE IDS

MDL Number MFCD00944907
CAS Number 149845-06-7

PROPERTIES

Empirical Formula (Hill Notation) C38H50N6O5·CH4O3S
Purity ≥98% (HPLC)
Apperance white to tan powder
Solubility DMSO: ≥5 mg/mL
MSDS Link Download
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent.
Description (简体中文)
Biochem/physiol Actions
Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent.

REFERENCES