Q-VD-OPh hydrate

• Catalog No.: SML0063
• CAS Number: 1135695-98-5(anhydrous)
• M. F.: C26H27F2N3O7
• M. W.: 531.5052864
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: (3S)-5-(2,6-difluorophenoxy)-3-[(2S)-3-methyl-2-(quinolin-2-ylformamido)butanamido]-4-oxopentanoic acid hydrate
• IUPAC Traditional name: (3S)-5-(2,6-difluorophenoxy)-3-[(2S)-3-methyl-2-(quinolin-2-ylformamido)butanamido]-4-oxopentanoic acid hydrate
• Synonyms: (3S)-5-(2,6-Difluorophenoxy)-3-[[(2S)-3-methyl-1-oxo-2-[(2-quinolinylcarbonyl)amino]butyl]amino]-4-oxo-pentanoic acid hydrate

DATABASE IDS

• MDL Number: MFCD20527311
• CAS Number: 1135695-98-5(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C26H25F2N3O6 · xH2O
• Purity: ≥95% (HPLC)
• Shipped in: wet ice
• Apperance: white to light brown powder
• Solubility: DMSO: ≥14 mg/mL
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Q-VD-OPh is a potent pan-caspase inhibitor that protects cells from capsase-dependent apoptosis. Q-VD-OPh has superior aqueous stability, cell permeability, and efficacy than FMK-based caspase inhibitors and displays no cytotoxic effects alone.

Description (简体中文)

Biochem/physiol Actions
Q-VD-OPh is a potent pan-caspase inhibitor that protects cells from capsase-dependent apoptosis. Q-VD-OPh has superior aqueous stability, cell permeability, and efficacy than FMK-based caspase inhibitors and displays no cytotoxic effects alone.