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SAHA

Catalog No. SML0061 Name Sigma Aldrich
CAS Number 149647-78-9 Website http://www.sigmaaldrich.com
M. F. C14H20N2O3 Telephone 1-800-521-8956
M. W. 264.3202 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 2276

SYNONYMS

IUPAC name
N-hydroxy-N'-phenyloctanediamide
IUPAC Traditional name
SAHA
Synonyms
N-hydroxy-N′-phenyl-octanediamide
suberoylanilide hydroxamic acid
vorinostat

DATABASE IDS

MDL Number MFCD00945317
CAS Number 149647-78-9

PROPERTIES

Empirical Formula (Hill Notation) C14H20N2O3
Purity ≥98% (HPLC)
Shipped in wet ice
Apperance white to tan powder
Solubility DMSO: ≥15 mg/mL
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H341-H360
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
GHS Precautionary statements P201-P281-P308 + P313
Risk Statements 61-68
Safety Statements 53-36/37-45
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Vorinostat or suberoylanilide hydroxamic acid (SAHA) is a potent, reversible pan-histone deacetylase (HDAC) inhibitor. It inhibits both class I and class II HDACs, altering gene transcription and inducing cell cycle arrest and/or apoptosis in a wide variety of transformed cells.
Description (简体中文)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Vorinostat or suberoylanilide hydroxamic acid (SAHA) is a potent, reversible pan-histone deacetylase (HDAC) inhibitor. It inhibits both class I and class II HDACs, altering gene transcription and inducing cell cycle arrest and/or apoptosis in a wide variety of transformed cells.

REFERENCES