Nifurtimox

• Catalog No.: N3415
• CAS Number: 23256-30-6
• M. F.: C10H13N3O5S
• M. W.: 287.29232
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 3-methyl-4-[2-(5-nitrofuran-2-yl)diazen-1-yl]-1λ^6-thiane-1,1-dione
• IUPAC Traditional name: 3-methyl-4-[2-(5-nitrofuran-2-yl)diazen-1-yl]-1λ^6-thiane-1,1-dione
• Synonyms: BAY 2502; 3-Methyl-4-(5′-nitrofurylidene-amino)-tetrahydro-4H-1,4-thiazine-1,1-dioxide; 4-((5-Nitrofurfurylidene)amino)-3-methylthiomorpholine 1,1-dioxide; Thiomorpholine, 3-methyl-4-((5-nitrofurfurylidene)amino)-,1,1-dioxide; (±)-Nifurtimox; (RS)-3-methyl-N-[(1E)-(5-nitro-2-furyl)methylene]thiomorpholin-4-amine 1,1-dioxide

DATABASE IDS

• CAS Number: 23256-30-6
• EC Number: 245-531-0

PROPERTIES

• Empirical Formula (Hill Notation): C10H13N3O5S
• Purity: ≥98% (HPLC)
• Apperance: yellow powder
• Solubility: DMSO: ≥13 mg/mL
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Nifurtimox is a nitrofurane derivative used to treat diseases caused by trypanosomes. Nifurtimox was discovered empirically and its mechanism of action is unclear. It is believed that nifurtimox exerts its biological activity through the bioreduction of the nitro-group to a nitro-anion radical which undergoes redox-cycling with molecular oxygen.

Description (简体中文)

Biochem/physiol Actions
Nifurtimox is a nitrofurane derivative used to treat diseases caused by trypanosomes. Nifurtimox was discovered empirically and its mechanism of action is unclear. It is believed that nifurtimox exerts its biological activity through the bioreduction of the nitro-group to a nitro-anion radical which undergoes redox-cycling with molecular oxygen.