Rosiglitazone

• Catalog No.: R2408
• CAS Number: 122320-73-4
• M. F.: C18H19N3O3S
• M. W.: 357.42676
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione
• IUPAC Traditional name: rosiglitazone
• Synonyms: rosiglitazone; 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione

DATABASE IDS

• MDL Number: MFCD00871760
• CAS Number: 122320-73-4

PROPERTIES

• Linear Formula: C18H19N3O3S
• Purity: ≥98% (HPLC)
• Purity: ≥98% (HPLC)
• Apperance: powder
• Solubility: DMSO: ≥10 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.

Description (简体中文)

Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.