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C646

Catalog No. SML0002 Name Sigma Aldrich
CAS Number 328968-36-1 Website http://www.sigmaaldrich.com
M. F. C24H19N3O6 Telephone 1-800-521-8956
M. W. 445.42416 Fax
Purity ≥98% (HPLC) Email
Storage desiccated Chembase ID: 154930

SYNONYMS

IUPAC name
4-(4-{[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene}-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
IUPAC Traditional name
4-(4-{[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene}-3-methyl-5-oxopyrazol-1-yl)benzoic acid
Synonyms
4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid

DATABASE IDS

CAS Number 328968-36-1
MDL Number MFCD01784780

PROPERTIES

Empirical Formula (Hill Notation) C24H19N3O6
Purity ≥98% (HPLC)
Apperance red to brown powder
Solubility DMSO: >25 mg/mL
GHS Pictograms GHS09
GHS Signal Word Warning
GHS Hazard statements H410
European Hazard Symbols Nature polluting Nature polluting (N)
MSDS Link Download
GHS Precautionary statements P273-P501
Risk Statements 50
Safety Statements 61
Storage Condition desiccated
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
C646 is a competitive histone acetyltransferase (HAT) p300/CBP inhibitor with a Ki of 400 nM and is selective versus other acetyltransferases.
Description (简体中文)
Biochem/physiol Actions
C646 is a competitive histone acetyltransferase (HAT) p300/CBP inhibitor with a Ki of 400 nM and is selective versus other acetyltransferases.

REFERENCES