L-α-Hydroxyglutaric acid disodium salt

• Catalog No.: 90790
• CAS Number: 63512-50-5
• M. F.: C5H6Na2O5
• M. W.: 192.07768
• Purity: ≥98.0% (GC)

SYNONYMS

• IUPAC name: disodium (2S)-2-hydroxypentanedioate
• IUPAC Traditional name: disodium L-2-hydroxyglutarate
• Synonyms: Disodium (S)-2-hydroxyglutarate; (S)-2-Hydroxypentanedioic acid disodium salt

DATABASE IDS

• Beilstein Number: 5318042
• CAS Number: 63512-50-5

PROPERTIES

• Impurities: ≤6.0% water
• Linear Formula: C5H6O5Na2
• Purity: ≥98.0% (GC)
• Optical Rotation: [α]/D -8.5±1.5°, c = 1 in 0.1 M NaOH
• Storage Temperature: 2-8°C

DETAILS

Description (English)

Biochem/physiol Actions
L-alpha-Hydroxyglutaric acid accumulates as a result of a rare defect in L-2-HG dehydogenase, leading to the metabolic disorder L-2-hydroxyglutaric aciduria (L-2HGA). L-2HGA is associated with neuronal defects, leukodystrophy and linked to an increased risk of brain tumors.

Description (简体中文)

Biochem/physiol Actions
L-alpha-Hydroxyglutaric acid accumulates as a result of a rare defect in L-2-HG dehydogenase, leading to the metabolic disorder L-2-hydroxyglutaric aciduria (L-2HGA). L-2HGA is associated with neuronal defects, leukodystrophy and linked to an increased risk of brain tumors.