SFLLR-NH2 trifluoroacetate salt

• Catalog No.: S8701
• M. F.: C32H52F3N9O8
• M. W.: 747.8059896
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-phenylpropanamido]-4-methylpentanamido]-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]-4-methylpentanamide; trifluoroacetic acid
• IUPAC Traditional name: (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-phenylpropanamido]-4-methylpentanamido]-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]-4-methylpentanamide; trifluoroacetic acid
• Synonyms: Ser-Phe-Leu-Leu-Arg-amide trifluoroacetate salt; Thrombin Receptor Activator for Peptide 5 (TRAP-5) trifluoroacetate salt; L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-Arginine amide trifluoroacetate salt

DATABASE IDS

• MDL Number: MFCD18782167

PROPERTIES

• Empirical Formula (Hill Notation): C30H51N9O6 · xC2HF3O2
• Purity: ≥95% (HPLC)
• Apperance: white to off-white powder
• Solubility: H2O: ≥2 mg/mL
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
SFLLR-NH2 is a PAR-1 (Protease-Activated Receptor) selective activating peptide, also known as Thrombin Receptor Activating Peptide 5 (TRAP-5). Protease-activated receptors (PARs) are present on various organs including, platelets, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing and proliferation of astrocytes.

Description (简体中文)

Biochem/physiol Actions
SFLLR-NH2 is a PAR-1 (Protease-Activated Receptor) selective activating peptide, also known as Thrombin Receptor Activating Peptide 5 (TRAP-5). Protease-activated receptors (PARs) are present on various organs including, platelets, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing and proliferation of astrocytes.