UK-356618

• Catalog No.: PZ0152
• CAS Number: 230961-08-7
• M. F.: C34H43N3O4
• M. W.: 557.72292
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2R)-N-[(1S)-2,2-dimethyl-1-{[(1R)-1-phenylethyl]carbamoyl}propyl]-N'-hydroxy-2-[3-(3-methyl-4-phenylphenyl)propyl]butanediamide
• IUPAC Traditional name: (2R)-N-[(1S)-2,2-dimethyl-1-{[(1R)-1-phenylethyl]carbamoyl}propyl]-N'-hydroxy-2-[3-(3-methyl-4-phenylphenyl)propyl]butanediamide
• Synonyms: (2R)-N1-[(1S)-2,2-Dimethyl-1-({[(1R)-1-phenylethyl]amino}carbonyl)propyl]-2-{3-[(3-methyl-4-phenyl)-phenyl]propyl}-(N4-hydroxy)butanediamide; UK-356,618

DATABASE IDS

• MDL Number: MFCD19443865
• CAS Number: 230961-08-7

PROPERTIES

• Empirical Formula (Hill Notation): C34H43N3O4
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Optical Rotation: [α]/D >+25.0°, c = 0.5 in methanol
• Solubility: DMSO: ≥25 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• German water hazard class: 3

DETAILS

Description (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
UK-356,618 is a potent, selective inhibitor of Matrix metalloproteinase MMP3 (stromelysin-1). MMP-3 IC50 = 5.9 nM, selectivity is 140-fold vs MMP-1, -2, -9, and -14.

Description (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
UK-356,618 is a potent, selective inhibitor of Matrix metalloproteinase MMP3 (stromelysin-1). MMP-3 IC50 = 5.9 nM, selectivity is 140-fold vs MMP-1, -2, -9, and -14.