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PD-180970_Molecular_structure_CAS_287204-45-9)
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PD-180970

Catalog No. PZ0142 Name Sigma Aldrich
CAS Number 287204-45-9 Website http://www.sigmaaldrich.com
M. F. C21H15Cl2FN4O Telephone 1-800-521-8956
M. W. 429.2744032 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154899

SYNONYMS

IUPAC name
6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
IUPAC Traditional name
6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7-one
Synonyms
6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one
PF-1515965

DATABASE IDS

MDL Number MFCD10565929
CAS Number 287204-45-9

PROPERTIES

Empirical Formula (Hill Notation) C21H15Cl2FN4O
Purity ≥98% (HPLC)
Apperance yellow
Solubility DMSO: >20 mg/mL
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301-H413
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
GHS Precautionary statements P301 + P310
Risk Statements 25
Safety Statements 45
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
PD-180970 is a potent inhibitor of the p210 Bcr-Abl tyrosine kinase.
Description (简体中文)
Biochem/physiol Actions
PD-180970 is a potent inhibitor of the p210 Bcr-Abl tyrosine kinase.

REFERENCES