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Zopolrestat

Catalog No. Z4527 Name Sigma Aldrich
CAS Number 110703-94-1 Website http://www.sigmaaldrich.com
M. F. C19H12F3N3O3S Telephone 1-800-521-8956
M. W. 419.3770896 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 6374

SYNONYMS

IUPAC name
2-(4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3,4-dihydrophthalazin-1-yl)acetic acid
IUPAC Traditional name
alond
Synonyms
3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid
Alond
Xedia
CP-73850

DATABASE IDS

MDL Number MFCD00865476
CAS Number 110703-94-1

PROPERTIES

Empirical Formula (Hill Notation) C19H12F3N3O3S
Purity ≥98% (HPLC)
Apperance off-white to light brown powder
Solubility DMSO: ≥20 mg/mL
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301-H413
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
GHS Precautionary statements P301 + P310
Risk Statements 25
Safety Statements 45
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Zopolrestat is an inhibitor of Aldose Reductase. AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.
Description (简体中文)
Biochem/physiol Actions
Zopolrestat is an inhibitor of Aldose Reductase. AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.

REFERENCES