Zopolrestat

• Catalog No.: Z4527
• CAS Number: 110703-94-1
• M. F.: C19H12F3N3O3S
• M. W.: 419.3770896
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-(4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3,4-dihydrophthalazin-1-yl)acetic acid
• IUPAC Traditional name: alond
• Synonyms: 3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid; Alond; Xedia; CP-73850

DATABASE IDS

• MDL Number: MFCD00865476
• CAS Number: 110703-94-1

PROPERTIES

• Empirical Formula (Hill Notation): C19H12F3N3O3S
• Purity: ≥98% (HPLC)
• Apperance: off-white to light brown powder
• Solubility: DMSO: ≥20 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H413
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P301 + P310
• Risk Statements: 25
• Safety Statements: 45
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Zopolrestat is an inhibitor of Aldose Reductase. AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.

Description (简体中文)

Biochem/physiol Actions
Zopolrestat is an inhibitor of Aldose Reductase. AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.