Vindesine sulfate salt hydrate

• Catalog No.: V4890
• CAS Number: 59917-39-4(anhydrous)
• M. F.: C43H59N5O12S
• M. W.: 870.01986
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: sulfuric acid hydrate methyl (13S,15S,17S)-13-[(1R,9R,10S,11R,12R,19R)-10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraene-13-carboxylate
• IUPAC Traditional name: sulfuric acid vindesine hydrate
• Synonyms: 3-(Aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine sulfate salt hydrate; Desacetylvinblastine amide sulfate salt hydrate

DATABASE IDS

• CAS Number: 59917-39-4(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C43H55N5O7 · H2SO4 · xH2O
• Purity: ≥95% (HPLC)
• Apperance: off-white to light yellow powder
• Solubility: deionized water: ≥50 mg/mL
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Microtubule inhibitor. Vindesine binds to and stabilizes tubulin, thereby preventing tubulin polymerization, preventing mitosis, and arresting cells in metaphase.

Description (简体中文)

Biochem/physiol Actions
Microtubule inhibitor. Vindesine binds to and stabilizes tubulin, thereby preventing tubulin polymerization, preventing mitosis, and arresting cells in metaphase.