Fleroxacin

• Catalog No.: F6807
• CAS Number: 79660-72-3
• M. F.: C17H18F3N3O3
• M. W.: 369.3383296
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: 氟罗沙星
• IUPAC name: 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• IUPAC Traditional name: fleroxacin
• Synonyms: 6,8-二氟-1-(2-氟乙基)1,4-二氢-7-(4-甲基-1-哌嗪基)-4-氧代-3-喹啉羧酸; 多氟沙星; 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid; AM-833; RO 23-6240; 6,8-Difluoro-1-(2-fluoroethyl)1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; Megalone; 6,8-二氟-1-(2-氟乙基)1,4-二氢-7-(4-甲基哌嗪)-4-氧代-3-喹啉羧酸; 多氟哌酸; Megalocin

DATABASE IDS

• CAS Number: 79660-72-3
• MDL Number: MFCD00864880

PROPERTIES

• Empirical Formula (Hill Notation): C17H18F3N3O3
• Purity: ≥98% (HPLC)
• Apperance: solid
• RTECS: VB1999050
• German water hazard class: 2

DETAILS

Description (English)

Application
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It is used in pharmacokinetic studies and is used to study the treatment of intra-abdominal abscesses and travellers’ diarrhea1,2,3.
Biochem/physiol Actions
Fleroxacin is a synthetic trifluorinated quinolone with antimicrobial activity against a variety of pathogens, including mycobacteria, mycoplasmas, chlamydiae, and legionellae. It strongly inhibits the DNA-supercoiling activity of DNA gyrase and DNA topoisomerase 2, which results in cell death4.

Description (简体中文)

Application
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It is used in pharmacokinetic studies and is used to study the treatment of intra-abdominal abscesses and travellers’ diarrhea1,2,3.
Biochem/physiol Actions
Fleroxacin is a synthetic trifluorinated quinolone with antimicrobial activity against a variety of pathogens, including mycobacteria, mycoplasmas, chlamydiae, and legionellae. It strongly inhibits the DNA-supercoiling activity of DNA gyrase and DNA topoisomerase 2, which results in cell death4.