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Sorbinil

Catalog No. S7701 Name Sigma Aldrich
CAS Number 68367-52-2 Website http://www.sigmaaldrich.com
M. F. C11H9FN2O3 Telephone 1-800-521-8956
M. W. 236.1991632 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 2434

SYNONYMS

IUPAC name
(4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-imidazolidine]-2',5'-dione
IUPAC Traditional name
sorbinil
Synonyms
(4S)-6-Fluoro-2,3-dihydro-spiro[4H-1-benzopyran-4,4′-imidazolidine]-2′,5′-dione
(+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione
CP 45634

DATABASE IDS

CAS Number 68367-52-2
MDL Number MFCD00867380

PROPERTIES

Empirical Formula (Hill Notation) C11H9FN2O3
Purity ≥98% (HPLC)
Apperance white to off-white powder
Optical Rotation [α]/D +50 to +60°, c = 1 in methanol
Solubility DMSO: ≥20 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Risk Statements 22
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Sorbinil is an inhibitor of Aldose Reductase (AR). AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.
Description (简体中文)
Biochem/physiol Actions
Sorbinil is an inhibitor of Aldose Reductase (AR). AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.

REFERENCES