Isoorientin

• Catalog No.: 02187
• CAS Number: 4261-42-1
• M. F.: C21H20O11
• M. W.: 448.3769
• Purity: ≥98.0% (HPLC)

SYNONYMS

• IUPAC name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen-4-one
• IUPAC Traditional name: isoorientin
• Synonyms: Luteolin 6-C-glucoside; Luteolin 6-C-β-D-glucoside; Homoorientin

DATABASE IDS

• MDL Number: MFCD00017433
• CAS Number: 4261-42-1

PROPERTIES

• Empirical Formula (Hill Notation): C21H20O11
• Purity: ≥98.0% (HPLC)
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
C-glycosyl flavone with anti-inflammatory, antimicrobial and antioxidant properties2. Induces antioxidant response through PI3K singaling.3
Luteolin, a common flavonoid, has been shown to inhibit secretion of ET-1 by porcine aortic endothelial cells at a 10 uM concentration. However, the luteolin glycoside compound, luteolin 6-C-glucoside, showed very weak inhibition of ET-1 release and inhibition only occurred at higher concentrations of luteolin 6-C-glucoside. 1

Description (简体中文)

Biochem/physiol Actions
C-glycosyl flavone with anti-inflammatory, antimicrobial and antioxidant properties2. Induces antioxidant response through PI3K singaling.3
Luteolin, a common flavonoid, has been shown to inhibit secretion of ET-1 by porcine aortic endothelial cells at a 10 uM concentration. However, the luteolin glycoside compound, luteolin 6-C-glucoside, showed very weak inhibition of ET-1 release and inhibition only occurred at higher concentrations of luteolin 6-C-glucoside. 1