Estropipate

• Catalog No.: E2661
• CAS Number: 477-24-7(freeacid)
• M. F.: C22H32N2O5S
• M. W.: 436.56488
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: [(1S,10R,11S,15S)-15-methyl-14-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-5-yl]oxidanesulfonic acid; piperazine
• IUPAC Traditional name: OGEN; piperazine
• Synonyms: 3-(Sulfooxy)-estra-1,3,5(10)-trien-17-one : piperazine (1:1); Harmogen; Ogen; Estrone sulfate piperazine salt; Estropipate

DATABASE IDS

• CAS Number: 477-24-7(freeacid)
• EC Number: 230-696-3
• MDL Number: MFCD00867399

PROPERTIES

• Empirical Formula (Hill Notation): C18H22O5S·C4H10N2
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Optical Rotation: [α]/D 100 to 120°, c = 1 in DMSO
• Solubility: DMSO: ≥24 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H350
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 45-22
• RTECS: KG7785000
• Safety Statements: 53-45
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Estropipate is the piperazine salt of the estrogen receptor agonist estrone-3-sulfate and a potent, specific inhibitor of the organic anion transporting polypeptide 1B1 (OATP1B1, IC50 = 60 nM).

Description (简体中文)

Biochem/physiol Actions
Estropipate is the piperazine salt of the estrogen receptor agonist estrone-3-sulfate and a potent, specific inhibitor of the organic anion transporting polypeptide 1B1 (OATP1B1, IC50 = 60 nM).