P7C3

• Catalog No.: D8446
• CAS Number: 301353-96-8
• M. F.: C21H18Br2N2O
• M. W.: 474.18842
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol
• IUPAC Traditional name: 1-(3,6-dibromocarbazol-9-yl)-3-(phenylamino)propan-2-ol
• Synonyms: 3,6-Dibromo-a-[(phenylamino)methyl]-9H-carbazole-9-ethanol

DATABASE IDS

• MDL Number: MFCD00572918
• CAS Number: 301353-96-8

PROPERTIES

• Empirical Formula (Hill Notation): C21H18Br2N2O
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Solubility: DMSO: soluble34 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H318
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P280-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25-41
• Safety Statements: 26-39-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
P7C3 is neurogenic and protects new neurons against apoptosis. These activities may be related to its capacity to protect mitochondrial integrity.Degeneration of the hippocampus is an early manifestation of Alzheimer′s disease. P7C3 promotes neurogenesis in the subgranular zone of the hippocampal dentate gyrus, the site of normal neurogenesis in adult mammals, making it an important lead compound in development of new Alzheimer′s treatments.1

Description (简体中文)

Biochem/physiol Actions
P7C3 is neurogenic and protects new neurons against apoptosis. These activities may be related to its capacity to protect mitochondrial integrity.Degeneration of the hippocampus is an early manifestation of Alzheimer′s disease. P7C3 promotes neurogenesis in the subgranular zone of the hippocampal dentate gyrus, the site of normal neurogenesis in adult mammals, making it an important lead compound in development of new Alzheimer′s treatments.1