JB1 trifluoroacetate salt

• Catalog No.: J3705
• CAS Number: 147819-32-7(freebase)
• M. F.: C55H88N14O15S2
• M. W.: 1249.50202
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: (3S,6S,9S,15S,18S,21S,24R,29R,32S,35S,38S,41S)-24-amino-3,35-bis(4-aminobutyl)-32-(hydroxymethyl)-21-[(4-hydroxyphenyl)methyl]-15,18,38-trimethyl-6-(2-methylpropyl)-2,5,8,14,17,20,23,31,34,37,40-undecaoxo-26,27-dithia-1,4,7,13,16,19,22,30,33,36,39-undecaazatricyclo[39.3.0.0^9,^1^3]tetratetracontane-29-carboxylic acid
• IUPAC Traditional name: (3S,6S,9S,15S,18S,21S,24R,29R,32S,35S,38S,41S)-24-amino-3,35-bis(4-aminobutyl)-32-(hydroxymethyl)-21-[(4-hydroxyphenyl)methyl]-15,18,38-trimethyl-6-(2-methylpropyl)-2,5,8,14,17,20,23,31,34,37,40-undecaoxo-26,27-dithia-1,4,7,13,16,19,22,30,33,36,39-undecaazatricyclo[39.3.0.0^9,^1^3]tetratetracontane-29-carboxylic acid
• Synonyms: H-Cys-Tyr-Ala-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Cys-OH trifluoroacetate salt; L-Cysteinyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-leucyl-L-lysyl-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-Cysteine, cyclic (1-12)-disulfide trifluoroacetate salt; JB-1 trifluoroacetate salt

DATABASE IDS

• CAS Number: 147819-32-7(freebase)
• MDL Number: MFCD00237120

PROPERTIES

• Empirical Formula (Hill Notation): C55H88N14O15S2 · xC2HF3O2
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: film
• Storage Condition: desiccated
• Storage Temperature: -20°C
• German water hazard class: nwg

DETAILS

Description (English)

Biochem/physiol Actions
JB1 is an IGF-I peptide analog; IGF-1 receptor antagonist. IGF-1, once known as somatomedin C, is involved in a multitude of activites including promoting growth and development, particularly neural development, and involved in the growth and proliferation in a variety of human cancers. JB1 is a 12-amino acid cyclic peptide, an IGF-1 analog, used by researchers in a variety of fields to inhibit IGF activity by inhibiting binding of IGF-1 to its receptor.

Description (简体中文)

Biochem/physiol Actions
JB1 is an IGF-I peptide analog; IGF-1 receptor antagonist. IGF-1, once known as somatomedin C, is involved in a multitude of activites including promoting growth and development, particularly neural development, and involved in the growth and proliferation in a variety of human cancers. JB1 is a 12-amino acid cyclic peptide, an IGF-1 analog, used by researchers in a variety of fields to inhibit IGF activity by inhibiting binding of IGF-1 to its receptor.