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Robinin

Catalog No. 53609 Name Sigma Aldrich
CAS Number 301-19-9 Website http://www.sigmaaldrich.com
M. F. C33H40O19 Telephone 1-800-521-8956
M. W. 740.6593 Fax
Purity ≥90.0% (HPLC) Email
Storage Chembase ID: 154806

SYNONYMS

IUPAC name
5-hydroxy-2-(4-hydroxyphenyl)-3-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-7-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-one
IUPAC Traditional name
robinin
Synonyms
Kaempferol 3-O-robinoside-7-O-rhamnoside

DATABASE IDS

EC Number 206-113-3
CAS Number 301-19-9

PROPERTIES

Safety Statements 22-24/25
Storage Temperature -20°C
German water hazard class 3
MSDS Link Download
Empirical Formula (Hill Notation) C33H40O19
Purity ≥90.0% (HPLC)

DETAILS

Description (English)
Biochem/physiol Actions
Flavone glycoside from Robinia with antibacterial1 and diuretic 2 properties; derived from kaempferol.3,4
The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry. 4
Description (简体中文)
Biochem/physiol Actions
Flavone glycoside from Robinia with antibacterial1 and diuretic 2 properties; derived from kaempferol.3,4
The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry. 4

REFERENCES