WR-1065

• Catalog No.: W2020
• CAS Number: 14653-77-1
• M. F.: C5H16Cl2N2S
• M. W.: 207.16494
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: 2-[(3-aminopropyl)amino]ethane-1-thiol dihydrochloride
• IUPAC Traditional name: 2-[(3-aminopropyl)amino]ethanethiol dihydrochloride
• Synonyms: WR-1065 dihydrochloride; 2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride

DATABASE IDS

• CAS Number: 14653-77-1
• MDL Number: MFCD00460339

PROPERTIES

• Empirical Formula (Hill Notation): C5H14N2S · 2HCl
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Solubility: H2O: ≥20 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H318
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P280-P305 + P351 + P338
• Risk Statements: 22-41
• Safety Statements: 26-39-41
• Storage Condition: desiccated
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

Description (简体中文)

Biochem/physiol Actions
WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.