Asenapine maleate

• Catalog No.: A7861
• CAS Number: 85650-56-2
• M. F.: C21H20ClNO5
• M. W.: 401.8402
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.0^2,^6.0^7,^1^2]octadeca-1(18),7,9,11,14,16-hexaene; but-2-enedioic acid
• IUPAC Traditional name: asenapine; butenedioic acid
• Synonyms: trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate; (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12btetrahydro-1Hdibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-butenedioate; Org 5222

DATABASE IDS

• EC Number: 288-064-8
• CAS Number: 85650-56-2

PROPERTIES

• Empirical Formula (Hill Notation): C17H16ClNO ·C4H4O4
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Solubility: H2O: ≥10 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335-H400
• European Hazard Symbols: Harmful (Xn)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P261-P273-P301 + P310-P305 + P351 + P338
• Risk Statements: 22-36/37/38-50/53
• Safety Statements: 26-60-61
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Asenapine maleate is a 5-HT receptor antagonist (5-HT1A,1B, 5-HT2A, 2B, 2C, 5-HT5A, 5-HT6 and 5-HT7), a D2 antagonist, and an antipsychotic.
Application
Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania.

Description (简体中文)

Biochem/physiol Actions
Asenapine maleate is a 5-HT receptor antagonist (5-HT1A,1B, 5-HT2A, 2B, 2C, 5-HT5A, 5-HT6 and 5-HT7), a D2 antagonist, and an antipsychotic.
Application
Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania.