Rifapentine

• Catalog No.: R0533
• CAS Number: 61379-65-5
• M. F.: C47H64N4O12
• M. W.: 877.03066
• Purity: ≥93%

SYNONYMS

• IUPAC name: (7S,12R,13S,14R,15R,16R,17S,18S)-26-[N-(4-cyclopentylpiperazin-1-yl)carboximidoyl]-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13-yl acetate
• IUPAC Traditional name: (7S,12R,13S,14R,15R,16R,17S,18S)-26-[N-(4-cyclopentylpiperazin-1-yl)carboximidoyl]-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13-yl acetate
• Synonyms: DL 473

DATABASE IDS

• CAS Number: 61379-65-5
• EC Number: 262-743-9

PROPERTIES

• Empirical Formula (Hill Notation): C47H64N4O2
• Purity: ≥93%
• Shipped in: wet ice
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: JQ0902000
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Rifapentine is an antibiotic clinically used to treat tuberculosis. It is used in tuberculosis research1.
Biochem/physiol Actions
Semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacterial and against Mycobacterium tuberculosis.2 Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription.3
Rifapentine is a semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacteria and against Mycobacterium tuberculosis. Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription. It interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme1.

Description (简体中文)

Application
Rifapentine is an antibiotic clinically used to treat tuberculosis. It is used in tuberculosis research1.
Biochem/physiol Actions
Semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacterial and against Mycobacterium tuberculosis.2 Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription.3
Rifapentine is a semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacteria and against Mycobacterium tuberculosis. Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription. It interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme1.