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Balsalazide disodium salt hydrate_Molecular_structure_CAS_213594-60-6(anhydrous))
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Balsalazide disodium salt hydrate

Catalog No. B5438 Name Sigma Aldrich
CAS Number 213594-60-6(anhydrous) Website http://www.sigmaaldrich.com
M. F. C17H15N3Na2O7 Telephone 1-800-521-8956
M. W. 419.29644 Fax
Purity ≥99% (HPLC) Email
Storage Chembase ID: 154786

SYNONYMS

IUPAC name
disodium 5-(2-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazen-1-yl)-2-hydroxybenzoate hydrate
IUPAC Traditional name
disodium 5-(2-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazen-1-yl)-2-hydroxybenzoate hydrate
Synonyms
5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate

DATABASE IDS

MDL Number MFCD18632541
CAS Number 213594-60-6(anhydrous)

PROPERTIES

Empirical Formula (Hill Notation) C17H13N3Na2O6 · xH2O
Purity ≥99% (HPLC)
MSDS Link Download
Storage Temperature 2-8°C
German water hazard class nwg

DETAILS

Description (English)
Biochem/physiol Actions
Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals.1 Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa.2 It was also shown to inhibit azoxymethane-induced colon carcinogenesis.3 In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).
Description (简体中文)
Biochem/physiol Actions
Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals.1 Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa.2 It was also shown to inhibit azoxymethane-induced colon carcinogenesis.3 In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

REFERENCES