Balsalazide disodium salt hydrate

• Catalog No.: B5438
• CAS Number: 213594-60-6(anhydrous)
• M. F.: C17H15N3Na2O7
• M. W.: 419.29644
• Purity: ≥99% (HPLC)

SYNONYMS

• IUPAC name: disodium 5-(2-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazen-1-yl)-2-hydroxybenzoate hydrate
• IUPAC Traditional name: disodium 5-(2-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazen-1-yl)-2-hydroxybenzoate hydrate
• Synonyms: 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate

DATABASE IDS

• MDL Number: MFCD18632541
• CAS Number: 213594-60-6(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C17H13N3Na2O6 · xH2O
• Purity: ≥99% (HPLC)
• Storage Temperature: 2-8°C
• German water hazard class: nwg

DETAILS

Description (English)

Biochem/physiol Actions
Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals.1 Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa.2 It was also shown to inhibit azoxymethane-induced colon carcinogenesis.3 In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

Description (简体中文)

Biochem/physiol Actions
Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals.1 Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa.2 It was also shown to inhibit azoxymethane-induced colon carcinogenesis.3 In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).