L-Homocysteine

• Catalog No.: 69453
• CAS Number: 6027-13-0
• M. F.: C4H9NO2S
• M. W.: 135.18476
• Purity: ≥98.0% (NT)

SYNONYMS

• IUPAC name: (2S)-2-amino-4-sulfanylbutanoic acid
• IUPAC Traditional name: L-homocysteine
• Synonyms: (S)-2-Amino-4-mercaptobutyric acid

DATABASE IDS

• CAS Number: 6027-13-0
• MDL Number: MFCD00151320
• EC Number: 227-891-0

PROPERTIES

• Linear Formula: HSCH2CH2CH(NH2)COOH
• Purity: ≥98.0% (NT)
• Optical Rotation: [α]/D 25.5±1.5°, c = 1 in 1 M HCl
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.1

Description (简体中文)

Biochem/physiol Actions
Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.1