Exemestane

• Catalog No.: PZ0006
• CAS Number: 107868-30-4
• M. F.: C20H24O2
• M. W.: 296.40336
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (1S,2R,10R,11S,15S)-2,15-dimethyl-8-methylidenetetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-5,14-dione
• IUPAC Traditional name: exemestane
• Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione

DATABASE IDS

• CAS Number: 107868-30-4
• MDL Number: MFCD00866994

PROPERTIES

• Empirical Formula (Hill Notation): C20H24O2
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Optical Rotation: [α]/D +250 to +300°, c = 1 in methanol
• Solubility: DMSO: ≥20 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H319-H360
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P201-P305 + P351 + P338-P308 + P313
• Risk Statements: 60-61-51
• Safety Statements: 53-22-36/37-57
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.

Description (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.