PHA-665752 hydrate

• Catalog No.: PZ0147
• CAS Number: 477575-56-7(anhydrous)
• M. F.: C32H36Cl2N4O5S
• M. W.: 659.62304
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 5-[(2,6-dichlorophenyl)methanesulfonyl]-3-({3,5-dimethyl-4-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1H-pyrrol-2-yl}methylidene)-2,3-dihydro-1H-indol-2-one hydrate
• IUPAC Traditional name: 5-[(2,6-dichlorophenyl)methanesulfonyl]-3-({3,5-dimethyl-4-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1H-pyrrol-2-yl}methylidene)-1H-indol-2-one hydrate
• Synonyms: (3Z)-5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-3-[[3,5-dimethyl-4-[[(2R)-2-(1-pyrrolidinylmethyl)-1-pyrrolidinyl]carbonyl]-1H-pyrrol-2-yl]methylene]-1,3-dihydro-2H-indol-2-one hydrate

DATABASE IDS

• CAS Number: 477575-56-7(anhydrous)
• MDL Number: MFCD18632554

PROPERTIES

• Empirical Formula (Hill Notation): C32H34Cl2N4O4S · xH2O
• Purity: ≥98% (HPLC)
• Apperance: light yellow to light brown powder
• Optical Rotation: [α]/D +50 to +70°, c = 0.2 in methanol
• Solubility: DMSO: ≥20 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-665752 ia a c-Met kinase inhibitor. PHA-665752 is ATP-competitive, an active-site inhibitor with greater than 50-fold selectivity for c-Met vs a panel of tyrosine and serine-threonine kinases.

Description (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-665752 ia a c-Met kinase inhibitor. PHA-665752 is ATP-competitive, an active-site inhibitor with greater than 50-fold selectivity for c-Met vs a panel of tyrosine and serine-threonine kinases.