SB 657510

• Catalog No.: S7326
• CAS Number: 474960-44-6
• M. F.: C19H22BrClN2O5S
• M. W.: 505.81038
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-bromo-N-(4-chloro-3-{[(3R)-1-methylpyrrolidin-3-yl]oxy}phenyl)-4,5-dimethoxybenzene-1-sulfonamide
• IUPAC Traditional name: 2-bromo-N-(4-chloro-3-{[(3R)-1-methylpyrrolidin-3-yl]oxy}phenyl)-4,5-dimethoxybenzenesulfonamide
• Synonyms: SB-657510; 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxy-benzenesulfonamide

DATABASE IDS

• CAS Number: 474960-44-6

PROPERTIES

• Empirical Formula (Hill Notation): C19H22BrClN2O5S
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Solubility: DMSO: ≥30 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
SB-657510 is a selective urotensin-II (UT) receptor antagonist. Human urotensin-II (hU-II) is proposed to play a significant role in cardiorenal and metabolic disease states, including heart failure, atherosclerosis, hypertension.

Description (简体中文)

Biochem/physiol Actions
SB-657510 is a selective urotensin-II (UT) receptor antagonist. Human urotensin-II (hU-II) is proposed to play a significant role in cardiorenal and metabolic disease states, including heart failure, atherosclerosis, hypertension.