Acepromazine maleate

• Catalog No.: A7111
• CAS Number: 3598-37-6
• M. F.: C23H26N2O5S
• M. W.: 442.52794
• Purity: ≥98% (HPLC)
• Storage: protect from light

SYNONYMS

• IUPAC name: 1-{10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one; but-2-enedioic acid
• IUPAC Traditional name: Ace; butenedioic acid
• Synonyms: Acepromazine maleate salt; Acetopromazine maleate salt; 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine maleate salt

DATABASE IDS

• CAS Number: 3598-37-6
• EC Number: 222-748-9
• MDL Number: MFCD00082473

PROPERTIES

• Empirical Formula (Hill Notation): C19H22N2OS · C4H4O4
• Purity: ≥98% (HPLC)
• Apperance: yellow powder
• Solubility: H2O: >10 mg/mL
• European Hazard Symbols: Harmful (Xn)
• European Hazard Symbols: Nature polluting (N)
• RID/ADR: UN 3077 9/PG 3
• Risk Statements: 22-50/53
• RTECS: OB2450000
• Safety Statements: 60-61
• Storage Condition: protect from light
• Storage Temperature: room temp
• Hazard Class: 9
• UN Number: 3077
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Application
Acepromazine is a phenothiazine and an analogue of the antipsychotic drug chlorpromazine (Cat. No. C8138). Acepromazine is thought to block dopamine receptors in the brain, and inhibit ABCG2 transport protein whose overexpression in tumors is associated with drug resistance.
Biochem/physiol Actions
Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine (#C8138). The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.

Description (简体中文)

Application
Acepromazine is a phenothiazine and an analogue of the antipsychotic drug chlorpromazine (Cat. No. C8138). Acepromazine is thought to block dopamine receptors in the brain, and inhibit ABCG2 transport protein whose overexpression in tumors is associated with drug resistance.
Biochem/physiol Actions
Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine (#C8138). The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.