Bisantrene dihydrochloride_Molecular_structure_CAS_78186-34-2)

add Bisantrene dihydrochloride to favorite

2D 3D Download Zoom

Bisantrene dihydrochloride
Catalog No.	B4563	Name	Sigma Aldrich
CAS Number	78186-34-2	Website	http://www.sigmaaldrich.com
M. F.	C22H24Cl2N8	Telephone	1-800-521-8956
M. W.	471.38556	Fax
Purity	≥98% (HPLC)	Email
Storage		Chembase ID: 154672

PRICE

Please log in

SYNONYMS

IUPAC name

2-{2-[(10-{[2-(4,5-dihydro-1H-imidazol-2-yl)hydrazin-1-ylidene]methyl}anthracen-9-yl)methylidene]hydrazin-1-yl}-4,5-dihydro-1H-imidazole dihydrochloride

IUPAC Traditional name

2-{2-[(10-{[2-(4,5-dihydro-1H-imidazol-2-yl)hydrazin-1-ylidene]methyl}anthracen-9-yl)methylidene]hydrazin-1-yl}-4,5-dihydro-1H-imidazole dihydrochloride

Synonyms

Bis((4,5-dihydro-1H-imidazol-2-yl)hydrazone)-9,10-anthracenedicarboxaldehyde dihydrochloride

NSC 337766

DATABASE IDS

CAS Number	78186-34-2
MDL Number	MFCD01743164

PROPERTIES

Empirical Formula (Hill Notation)	C22H22N8 ·2HCl
Purity	≥98% (HPLC)
Apperance	solid
Solubility	deionized water: soluble8 mg/mL
GHS Pictograms
GHS Pictograms
GHS Signal Word	Warning
GHS Hazard statements	H302-H400
European Hazard Symbols	Harmful (Xn)
European Hazard Symbols	Nature polluting (N)
MSDS Link	Download
GHS Precautionary statements	P273
RID/ADR	UN 2811 6.1/PG 3
Risk Statements	22-50/53
Safety Statements	60-61
Storage Temperature	room temp
Hazard Class	6.1
UN Number	2811
Packing Group	3
German water hazard class	3

DETAILS

Description (English)

Biochem/physiol Actions
Bisantrene dihydrochloride is an antineoplastic agent, MDR1 substrate, DNA intercalator, and topoisomerase II poison. Cancer cells that develop resistance to bisantrene tend to overexpress P-glycoprotein. Bisantrene can be used to select for P-glycoprotein-mediated multiple drug resistance. The data suggest that bisantrene is an excellent substrate for P-glycoprotein.1

Description (简体中文)