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Linezolid

Catalog No. PZ0014 Name Sigma Aldrich
CAS Number 165800-03-3 Website http://www.sigmaaldrich.com
M. F. C16H20FN3O4 Telephone 1-800-521-8956
M. W. 337.3461032 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 483

SYNONYMS

IUPAC name
N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
IUPAC Traditional name
linezolid
Synonyms
PNU-100766
N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
U-100766

DATABASE IDS

CAS Number 165800-03-3
MDL Number MFCD00937825

PROPERTIES

Empirical Formula (Hill Notation) C16H20FN3O4
Purity ≥98% (HPLC)
Target Organ Bone
Apperance white to off-white powder
Solubility DMSO: >20 mg/mL
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H372
MSDS Link Download
GHS Precautionary statements P314
RTECS AC2720000
Storage Temperature room temp
German water hazard class 3

DETAILS

Description (English)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Linezolid is an oxazolidinone antimicrobial. It binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.
Description (简体中文)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Linezolid is an oxazolidinone antimicrobial. It binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.

REFERENCES