RepSox

• Catalog No.: R0158
• CAS Number: 446859-33-2
• M. F.: C17H13N5
• M. W.: 287.31862
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
• IUPAC Traditional name: 2-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
• Synonyms: E-616452; 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine

DATABASE IDS

• MDL Number: MFCD09037561
• CAS Number: 446859-33-2

PROPERTIES

• Empirical Formula (Hill Notation): C17H13N5
• Purity: ≥98% (HPLC)
• Apperance: solid
• Solubility: DMSO: >20 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• Safety Statements: 45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3

DETAILS

Description (English)

Biochem/physiol Actions
RepSox Inhibits TGF-beta receptor signaling. Retroviral transduction of Sox2, Oct4, and Klf4 genes results in direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs).

Description (简体中文)

Biochem/physiol Actions
RepSox Inhibits TGF-beta receptor signaling. Retroviral transduction of Sox2, Oct4, and Klf4 genes results in direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs).