L-798106

• Catalog No.: L4545
• CAS Number: 244101-02-8
• M. F.: C27H22BrNO4S
• M. W.: 536.43688
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-(5-bromo-2-methoxybenzenesulfonyl)-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide
• IUPAC Traditional name: N-(5-bromo-2-methoxybenzenesulfonyl)-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide
• Synonyms: (2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide

DATABASE IDS

• MDL Number: MFCD08272644
• CAS Number: 244101-02-8

PROPERTIES

• Empirical Formula (Hill Notation): C27H22BrNO4S
• Purity: ≥98% (HPLC)
• Apperance: powder
• Solubility: DMSO: >20 mg/mL
• GHS Hazard statements: H413
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
L-798106 was among the first prostanoid receptor EP3-selective antagonists. It has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. It successfully blocks the actions of sulprostone, an EP3-selective agonist, and it helped show that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity.1

Description (简体中文)

Biochem/physiol Actions
L-798106 was among the first prostanoid receptor EP3-selective antagonists. It has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. It successfully blocks the actions of sulprostone, an EP3-selective agonist, and it helped show that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity.1