DPPE hydrochloride

• Catalog No.: D2571
• CAS Number: 92981-78-7
• M. F.: C19H26ClNO
• M. W.: 319.86884
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: [2-(4-benzylphenoxy)ethyl]diethylamine hydrochloride
• IUPAC Traditional name: [2-(4-benzylphenoxy)ethyl]diethylamine hydrochloride
• Synonyms: BMS-217380-01; Tesmilifene hydrochloride; YMB1002; N,N-Diethyl-2-[4-(phenylmethyl) phenoxy]ethanamine hydrochloride; [2-(4-Benzyl-phenoxy)-ethyl]-diethyl-amine hydrochloride

DATABASE IDS

• MDL Number: MFCD11114012
• CAS Number: 92981-78-7

PROPERTIES

• Empirical Formula (Hill Notation): C19H25NO·HCl
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: H2O: soluble16 mg/mL
• RID/ADR: UN 3077 9/PG 3
• Storage Temperature: 2-8°C
• Hazard Class: 9
• UN Number: 3077
• Packing Group: 3
• German water hazard class: nwg

DETAILS

Description (English)

Biochem/physiol Actions
DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site.

Description (简体中文)

Biochem/physiol Actions
DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site.