(4R)-4-Hydroxy-L-glutamic acid

• Catalog No.: 76157
• CAS Number: 2485-33-8
• M. F.: C5H9NO5
• M. W.: 163.12866
• Purity: ≥98.0% (TLC)

SYNONYMS

• IUPAC name: (2S,4R)-2-amino-4-hydroxypentanedioic acid
• IUPAC Traditional name: (2S,4R)-2-amino-4-hydroxypentanedioic acid
• Synonyms: H-(2S,4R)-γ-Hydroxy-Glu-OH; erythro-(4R)-4-Hydroxy-L-glutamic acid

DATABASE IDS

• MDL Number: MFCD00672375
• CAS Number: 2485-33-8
• Beilstein Number: 1725871

PROPERTIES

• Empirical Formula (Hill Notation): C5H9NO5
• Purity: ≥98.0% (TLC)
• Optical Rotation: [α]/D 20.5±1.5°, c = 1 in H2O
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptors, mGlu1a, mGlu2, and mGlu8a in a dose-dependent manner. 1
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 76157.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

Biochem/physiol Actions
(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptors, mGlu1a, mGlu2, and mGlu8a in a dose-dependent manner. 1
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 76157.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.