N-Methyl-cis-4-hydroxy-L-proline

• Catalog No.: 80351
• CAS Number: 67463-44-9
• M. F.: C6H11NO3
• M. W.: 145.15644
• Purity: ≥98.0% (TLC)

SYNONYMS

• Title: N-甲基-顺-4-羟基-L-脯氨酸
• IUPAC name: (2S,4S)-4-hydroxy-1-methylpyrrolidine-2-carboxylic acid
• IUPAC Traditional name: (2S,4S)-4-hydroxy-1-methylpyrrolidine-2-carboxylic acid
• Synonyms: N-甲基-L-别羟脯氨酸; (4S)-4-羟基-1-甲基-L-脯氨酸; (4S)-4-Hydroxy-1-methyl-L-proline; N-Me-cis-Hyp-OH; N-Methyl-L-allohydroxyproline

DATABASE IDS

• CAS Number: 67463-44-9
• MDL Number: MFCD02094307

PROPERTIES

• Empirical Formula (Hill Notation): C6H11NO3
• Purity: ≥98.0% (TLC)
• Optical Rotation: [α]/D -68.5±2.5°, c = 1 in H2O
• GHS Signal Word: Warning
• GHS Hazard statements: H317-H319
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P280-P305 + P351 + P338
• Risk Statements: 36-43
• Safety Statements: 26-36/37
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.

Description (简体中文)

Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.