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N-Methyl-L-norvaline_Molecular_structure_CAS_19653-78-2)
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N-Methyl-L-norvaline

Catalog No. 04858 Name Sigma Aldrich
CAS Number 19653-78-2 Website http://www.sigmaaldrich.com
M. F. C6H13NO2 Telephone 1-800-521-8956
M. W. 131.17292 Fax
Purity ≥98% (TLC) Email
Storage Chembase ID: 154621

SYNONYMS

IUPAC name
(2S)-2-(methylamino)pentanoic acid
IUPAC Traditional name
(2S)-2-(methylamino)pentanoic acid
Synonyms
N-Me-Nva-OH
(S)-2-(Methylamino)pentanoic acid

DATABASE IDS

Beilstein Number 4739047
CAS Number 19653-78-2
MDL Number MFCD02094305

PROPERTIES

Compostion carbon, 54.1-55.7%
Compostion nitrogen, 10.4-10.9%
Empirical Formula (Hill Notation) C6H13NO2
Purity ≥98% (TLC)
Optical Rotation [α]/D +24.0±1.0°, c = 1 in 1 M HCl
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H319
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
GHS Precautionary statements P305 + P351 + P338
Risk Statements 36
Safety Statements 26
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.
Description (简体中文)
Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.

REFERENCES