N-Methyl-L-threonine

• Catalog No.: 55345
• CAS Number: 2812-28-4
• M. F.: C5H11NO3
• M. W.: 133.14574
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: (2S,3R)-3-hydroxy-2-(methylamino)butanoic acid
• IUPAC Traditional name: (2S,3R)-3-hydroxy-2-(methylamino)butanoic acid
• Synonyms: N-Me-Thr-OH; (2S,3R)-3-Hydroxy-2-(methylamino)butyric acid

DATABASE IDS

• Beilstein Number: 1722279
• MDL Number: MFCD02094308
• CAS Number: 2812-28-4

PROPERTIES

• Compostion: carbon, 44.2-46.0%
• Compostion: nitrogen, 10.3-10.8%
• Empirical Formula (Hill Notation): C5H11NO3
• Purity: ≥98% (TLC)
• Optical Rotation: [α]/D -24.0±1.0°, c = 1 in 1 M HCl
• GHS Signal Word: Warning
• GHS Hazard statements: H319
• GHS Precautionary statements: P305 + P351 + P338
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.

Description (简体中文)

Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.