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N-Methyl-L-valine_Molecular_structure_CAS_2480-23-1)
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N-Methyl-L-valine

Catalog No. 90119 Name Sigma Aldrich
CAS Number 2480-23-1 Website http://www.sigmaaldrich.com
M. F. C6H13NO2 Telephone 1-800-521-8956
M. W. 131.17292 Fax
Purity ≥98% (TLC) Email
Storage Chembase ID: 154615

SYNONYMS

IUPAC name
(2S)-3-methyl-2-(methylamino)butanoic acid
IUPAC Traditional name
(2S)-3-methyl-2-(methylamino)butanoic acid
Synonyms
N-Me-Val-OH
(S)-3-Methyl-2-(methylamino)butyric acid

DATABASE IDS

CAS Number 2480-23-1
MDL Number MFCD00037754
Beilstein Number 1721712

PROPERTIES

Compostion carbon, 54.1-55.7%
Compostion nitrogen, 10.4-11.0%
Empirical Formula (Hill Notation) C6H13NO2
Purity ≥98% (TLC)
Optical Rotation [α]/D +25.0±1.0°, c = 1 in 1 M HCl
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H319
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
GHS Precautionary statements P305 + P351 + P338
Risk Statements 36
Safety Statements 26
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.
Description (简体中文)
Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease1, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.

REFERENCES