Dexrazoxane

• Catalog No.: D1446
• CAS Number: 24584-09-6
• M. F.: C11H16N4O4
• M. W.: 268.26914
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
• IUPAC Traditional name: dexrazoxane
• Synonyms: NSC169780; Icrf-187; Cardioxane; (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; (+)-(S)-4,4′-Propylenedi-2,6-piperazinedione; Zinecard

DATABASE IDS

• MDL Number: MFCD00866449
• CAS Number: 24584-09-6

PROPERTIES

• Empirical Formula (Hill Notation): C11H16N4O4
• Purity: ≥95% (HPLC)
• Apperance: white to off-white powder
• Solubility: DMSO: >20 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: room temp
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Dexrazoxane is a cardioprotective compound against anthracyclines. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.

Description (简体中文)

Biochem/physiol Actions
Dexrazoxane is a cardioprotective compound against anthracyclines. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.