CP-380736

• Catalog No.: PZ0129
• CAS Number: 179688-29-0
• M. F.: C14H18N2O5
• M. W.: 294.30312
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 6,7-bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one
• IUPAC Traditional name: 6,7-bis(2-methoxyethoxy)-3H-quinazolin-4-one
• Synonyms: PF-00520893; 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone; 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one

DATABASE IDS

• MDL Number: MFCD02678087
• CAS Number: 179688-29-0

PROPERTIES

• Empirical Formula (Hill Notation): C14H18N2O5
• Purity: ≥98% (HPLC)
• Apperance: off-white to light tan powder
• Solubility: DMSO: ≥10 mg/mL
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

Description (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.