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Dofetilide

Catalog No. PZ0016 Name Sigma Aldrich
CAS Number 115256-11-6 Website http://www.sigmaaldrich.com
M. F. C19H27N3O5S2 Telephone 1-800-521-8956
M. W. 441.56478 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 89

SYNONYMS

IUPAC name
N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
IUPAC Traditional name
N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
Synonyms
UK-68798
N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]methanesulfonamide

DATABASE IDS

CAS Number 115256-11-6
MDL Number MFCD00869707

PROPERTIES

Empirical Formula (Hill Notation) C19H27N3O5S2
Purity ≥98% (HPLC)
Apperance white to off-white powder
Solubility DMSO: >20 mg/mL
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H302-H360
European Hazard Symbols Toxic Toxic (T)
European Hazard Symbols Nature polluting Nature polluting (N)
MSDS Link Download
GHS Precautionary statements P201-P308 + P313
Risk Statements 61-48/22-51
Safety Statements 53-22-36-57
Storage Temperature room temp
German water hazard class nwg

DETAILS

Description (English)
Biochem/physiol Actions
Dofetilide is a Class III antiarrhythmic and hERG channel blocker. Dofetilide selectively blocks the rapid component of the delayed rectifier outward potassium current (IKr).
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Description (简体中文)
Biochem/physiol Actions
Dofetilide is a Class III antiarrhythmic and hERG channel blocker. Dofetilide selectively blocks the rapid component of the delayed rectifier outward potassium current (IKr).
Legal Information
Sold for research purposes under agreement from Pfizer Inc.

REFERENCES