Voriconazole

• Catalog No.: PZ0005
• CAS Number: 137234-62-9
• M. F.: C16H14F3N5O
• M. W.: 349.3104696
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
• IUPAC Traditional name: voriconazole
• Synonyms: UK-109496; 2R,3S-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

DATABASE IDS

• MDL Number: MFCD00905717
• CAS Number: 137234-62-9

PROPERTIES

• Empirical Formula (Hill Notation): C16H14F3N5O
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: DMSO: >20 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H351-H361-H373-H412
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P273-P281-P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 61-25-40-48/22-52/53
• RTECS: UV9145000
• Safety Statements: 53-22-36/37-45
• Storage Temperature: room temp
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.

Description (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.