Atorvastatin calcium salt trihydrate

• Catalog No.: PZ0001
• CAS Number: 134523-03-8(anhydrous)
• M. F.: C66H74CaF2N4O13
• M. W.: 1209.3875664
• Purity: ≥98% (HPLC)
• Storage: protect from light

SYNONYMS

• IUPAC name: trihydrate {[(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl]oxy}calcio (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: trihydrate {[(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoyl]oxy}calcio (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoate

DATABASE IDS

• MDL Number: MFCD09752074
• CAS Number: 134523-03-8(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C33H34FN2O5 · 0.5 Ca · 1.5 H2O
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: DMSO: ≥10 mg/mL
• Storage Condition: protect from light
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Atorvastatin calcium salt trihydrate is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.

Description (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Atorvastatin calcium salt trihydrate is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.