Oroxylin A

• Catalog No.: O0641
• CAS Number: 480-11-5
• M. F.: C16H12O5
• M. W.: 284.26348
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 5,7-dihydroxy-6-methoxy-2-phenyl-4H-chromen-4-one
• IUPAC Traditional name: oroxylin A
• Synonyms: 5,7-Dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one; 6-Methoxybaicalein;; 5,7-Dihydroxy-6-methoxyflavone;

DATABASE IDS

• CAS Number: 480-11-5
• MDL Number: MFCD02259441

PROPERTIES

• Empirical Formula (Hill Notation): C16H12O5
• Purity: ≥98% (HPLC)
• Apperance: yellow powder
• Solubility: DMSO: ≥20 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Oroxylin A is a flavonoid isolated from Scutellaria baicalensis, which is one of the most important medicinal herbs in traditional Korean/Chinese/Japanese medicine. The amelioration of Abeta(25-35) peptide-induced memory impairment by oroxylin A is believed to be mediated via the GABAergic neurotransmitter system after a single administration, or by reductions in Abeta(25-35) peptide-induced astrocyte and microglia activations, iNOS expression, lipid peroxidation, and increased cholinergic neurotransmission after subchronic administration.

Description (简体中文)

Biochem/physiol Actions
Oroxylin A is a flavonoid isolated from Scutellaria baicalensis, which is one of the most important medicinal herbs in traditional Korean/Chinese/Japanese medicine. The amelioration of Abeta(25-35) peptide-induced memory impairment by oroxylin A is believed to be mediated via the GABAergic neurotransmitter system after a single administration, or by reductions in Abeta(25-35) peptide-induced astrocyte and microglia activations, iNOS expression, lipid peroxidation, and increased cholinergic neurotransmission after subchronic administration.