NVP-231

• Catalog No.: N9289
• CAS Number: 362003-83-6
• M. F.: C25H25N3O2S
• M. W.: 431.5499
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (3R,5S,7s)-N-(2-benzamido-1,3-benzothiazol-6-yl)adamantane-1-carboxamide
• IUPAC Traditional name: (3R,5S,7s)-N-(2-benzamido-1,3-benzothiazol-6-yl)adamantane-1-carboxamide
• Synonyms: N-[2-(benzoylamino)-6-benzothiazolyl]-Tricyclo[3.3.1.13,7]decane-1-carboxamide; adamantane-1-carboxylic acid (2-benzoylamino-benzothiazol-6-yl)amide

DATABASE IDS

• CAS Number: 362003-83-6
• MDL Number: MFCD01988824

PROPERTIES

• Empirical Formula (Hill Notation): C25H25N3O2S
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Solubility: DMSO: >10 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: nwg

DETAILS

Description (English)

Biochem/physiol Actions
Ceramide kinase presents an attractive target for drug development because of its involvement in cell growth and inflammation. CerK biology is still poorly understood thus discovery and availability of inhibitors will facilitate research at this area. NVP-231 is a newly discovered potent, specific and reversible CerK inhibitor that competitively inhibits binding of ceraminde to CerK.

Description (简体中文)

Biochem/physiol Actions
Ceramide kinase presents an attractive target for drug development because of its involvement in cell growth and inflammation. CerK biology is still poorly understood thus discovery and availability of inhibitors will facilitate research at this area. NVP-231 is a newly discovered potent, specific and reversible CerK inhibitor that competitively inhibits binding of ceraminde to CerK.